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Tom
Member
Username: Dad

Post Number: 1
Registered: 09-2010
Posted on Monday, September 06, 2010 - 06:22 pm:   Edit Post Delete Post Print Post

Heart tx 6 weeks ago. Now diabetes. Any of you had islet cell transplant to rx diabetes after transplant?
Karen R.
Forum Leader
Username: Relivkaren

Post Number: 4791
Registered: 07-2007
Posted on Monday, September 06, 2010 - 09:28 pm:   Edit Post Delete Post Print Post

Tom:

Welcome to Transplant Buddies! Congratulations on your new heart transplant.

Yes - many people get drugged induced diabetes post transplant. I have been blessed not to have diabetes. I do watch my diet very closely, but as some will tell you that doesn't always work.

I am sure that you will hear from others that have had the same issues that you are dealing with. Many people find that once the meds are reduced or adjusted that the diabetes improves or goes away. Not always, but diabetes can be managed with meds and diet.

I hope you continue to visit. We look forward to getting to know you.

God Bless!
Karen
Dx: BOOP - May 2006. Rediagnosed with Bronchiolitis Obliterans Nov. 2006
Double lung transplant on Dec. 1st, 2009
Cleveland Clinic

Ohio, USA

Be kinder than necessary because everyone you meet is fighting some kind of battle.
BreathinSteven
Forum Leader
Username: Breathinsteven

Post Number: 2148
Registered: 11-2004
Posted on Monday, September 06, 2010 - 09:38 pm:   Edit Post Delete Post Print Post

Hi Tom!

Where did you hear that islet cell transplant would work post transplant for what is likely transplant medication related diabetes? I'd never really heard anyone suggest that before...

I was diagnosed diabetic about 10 weeks post transplant -- though my blood glucose levels were all over the place from immediately after transplant... My guess is that I was most highly impacted by the prednisone -- but the Prograf/tacrolimus is often a contributing factor as well...

My vague understanding is that we've got a kinda double-whammy going -- the drugs may inhibit our insulin production -- and they often also increase our insulin resistance... Our pancreas may still be pumping out insulin, though maybe not as much as we need -- and our cells are blocking it from being used properly...

I've been on insulin therapy for 10 years now -- since weeks after my transplant... Currently, I'm on Lantus and Humalog... As Karen pointed out -- my insulin needs reduced drastically when they reduced my meds 6-12 months out -- but mine did not go away... I've known many other recipients who no longer needed insulin months or even a year or two after transplant...

I would be interested in hearing where you heard that islet cell transplant was a possible solution post organ transplant to address this kind of diabetes... Let us know...

Love, Steve
Steve
CF, Dbl-Lung Recip April 2000
www.ClimbingForKari.org
www.ReviveHope.com

www.youtube.com/SteveFerkau

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