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babeshmeb
Member
Username: Babeshmeb

Post Number: 9
Registered: 02-2012
Posted on Wednesday, March 28, 2012 - 03:20 pm:   Edit Post Delete Post Print Post

What is the normal trough levels for Prograf?
Has anyone has any rejection episodes?
CiscoKidney07
Forum Leader
Username: Gregg

Post Number: 5403
Registered: 03-2008
Posted on Wednesday, March 28, 2012 - 06:09 pm:   Edit Post Delete Post Print Post

Actually trough levels vary from person to person. It also makes a difference what medications you are taking. Some folks take more kinds of meds than others do. I have not had a rejection episode. I take Prograf 2mg a.m. and 2 mg p.m., Prednisone 2.5 mg. Some folks take Cellcept, but I do not. They might also take something in place of prograf.
If you are going through hell, keep going-Winston Churchill

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Holly
Member
Username: Holly

Post Number: 581
Registered: 09-2007
Posted on Wednesday, March 28, 2012 - 07:35 pm:   Edit Post Delete Post Print Post

I take 2mg prograg AM and PM and also 750mg cellcept Am and PM. I was on 1.5 prograf twice a day and 250 cellcept twice a day and I did go into cellular rejection in Nov. Was treated with HIGH dose of prednisone and my immunosuppressants were taken up...so far I am out of rejection now but was told once you have a rejection episode you are at higher risk for having it again. i think it's different for everyone.They try to keep you at a level that keeps your immune system just at that level to keep you from rejecting...it's a fine line we all have to walk.
Holly Mulkerin
Medina Ohio
Heart transplant 1/28/09 I have a Happy Heart
Be kind. Remember that everyone you meet is fighting a hard battle. Harry Thompson

Jack
Forum Leader
Username: Johnhollenbach56

Post Number: 566
Registered: 12-2009
Posted on Wednesday, March 28, 2012 - 09:02 pm:   Edit Post Delete Post Print Post

I no longer take Prograf - my Dr. Feels that Rapamune is friendlier to the kidney, he made the switch for me after my first annual. I also take Cellecept and Prednisone. A lot depends on age, underlying conditions, and other physical factors. Don't think we have many (at my center) that share the same doseages/drug cocktails . . .
Jack Hollenbach
Received double lung transplant August 2 & 3, 2007 for COPD at UCSD Thornton Hospital, San Diego, CA

Live each day to your fullest, for it is a gift to be treasured
papillonbleu
Forum Leader
Username: Papillonbleu

Post Number: 2187
Registered: 10-2007
Posted on Thursday, March 29, 2012 - 07:24 am:   Edit Post Delete Post Print Post

I have been on Prograf since my transplant. The trough level desired is probably different for each person depending on the circumstances. Mine usually stays around 4-6 and I am on 2mg twice a day. My doctors have said I have had some minor rejection episodes but nothing really serious. Best of wishes to you.
Bobbiejo
Forum Leader-Multivisceral
dx: GERD 1995, gastroparesis 2002, pseudo-obstruction of the bowel 2004
multivisceral transplant, 6 organs, 10/06/05
University of Miami/Jackson Memorial Hospital

Rocket Heart
Member
Username: Rocketheart583

Post Number: 645
Registered: 08-2007
Posted on Thursday, March 29, 2012 - 09:11 am:   Edit Post Delete Post Print Post

Prograf trough levels vary as you progress with your transplant. They are initially high and gradually are reduced depending on the results of your blood work, which you should have about every 6 weeks.

I have been on Prograf for over 7 years - no rejection episodes thus far. I do know that there is a protocol for this medication and it does vary somewhat with each patient. I am currently between 5 - 6 and have been steady for some time now. 2mg am/pm.

Hope this helped.
Rocket Heart

Tom Emahiser
Waterville, Oh
Heart Failure
Heart Txplt 1/26/05 University of Michigan

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