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TransplantBuddies.org Forums » Kidney - Pancreas Transplant » Missed meds/donor match %? « Previous Next »
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Skye
Member
Username: Skye4296

Post Number: 2
Registered: 04-2014
Posted on Wednesday, April 30, 2014 - 01:57 am:   Edit Post Delete Post Print Post

Bit of a veteran (14yr k/p transplant) and have had to miss my medications several times - the longest was 3 days worth. I've asked my doctor to tell me what the percentage match was between myself and my donor but he just dodges answering me "oh goodness that's buried in the records somewhere" etc. While I was on dialysis, several patients had said they only missed one dose and they lost the transplant.
Does this mean I'm probably a close match? Is there a data base that I can access to find out how close a match my donor (cadaver) and I were?}
Cora
Member
Username: Cora

Post Number: 551
Registered: 06-2007
Posted on Wednesday, April 30, 2014 - 02:09 pm:   Edit Post Delete Post Print Post

This is personal opinion only, based on what I know of my transplant and those of a few friends (as well as my biology degree). There is no direct correlation between match and rejection. Not any more and not with modern transplant meds. Take me for example. My cousin and I were a 1/6 match. I've had my gift almost 12 years now and over a few years I had tremendous gastric issues and vomited a lot (sometimes for months on end). I can't imagine how inconsistent my drug absorption was. And (knock on wood) I've never had an episode of rejection.

Rejection isn't anywhere near as simple as drug level/consistency versus degree of matching. For example, you may come in contact with something (blood transfusion, infection, virus) that can cause your immune system to react. Will it react, once on high alert, to your kidney? The answer is that they just don't know exactly what triggers a rejection. And then there is acute rejection versus chronic rejection. Again, 2 different things.

The best you can do is improve your odds by taking your drugs as regularly as you can and to try to avoid getting sick.

The rest is up to God (if you are a believer) and nature. And neither is truly understood.
Dx with T1 in 1966
Kidney tx in Minneapolis 2002
Pancreas tx in 2008
nish
Member
Username: Rickysyfee

Post Number: 156
Registered: 06-2008
Posted on Wednesday, April 30, 2014 - 07:45 pm:   Edit Post Delete Post Print Post

Cora,

Very well put! I agree, I have missed doses many times before, even called the nurse to tell her. They were not concerned
Transplant~7/01 (living donor)
Dialysis- CAPD, APD,In center hemo and SIHD
Transplant~ 8/07 (deceased donor)

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